HAAO

Across TCGA cell cohorts, HAAO RNA expression is significantly associated with the go_rna of many other GO terms, with 2,642 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HAAO-associated GO terms across cancer lineages are Dicarboxylic acid biosynthetic process, Quinolinate biosynthetic process, and Cholesterol biosynthetic process via lathosterol. Each is linked with HAAO in more than 6 cancer types. Because this analysis shows association rather than direction, both HAAO-to-partner and partner-to-HAAO results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dicarboxylic acid biosynthetic process grouped by HAAO-low versus HAAO-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HAAO→partner) and Y-score (partner→HAAO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Dicarboxylic acid biosynthetic process →	-0.222	-1.109	<.001	.006	2	7
STOMACH	Quinolinate biosynthetic process →	+1.547	+3.146	<.001	<.001	3	6
BLOOD_Lymphoma	Cholesterol biosynthetic process via lathosterol →	+0.130	+2.008	<.001	<.001	3	6
BLOOD_Leukemia	Regulation of regulatory T cell differentiation →	+0.058	+1.439	.007	.001	2	7
BREAST	Microtubule bundle formation →	-0.043	-1.363	<.001	.001	3	5
BREAST	T cell activation involved in immune response →	+0.111	+1.245	<.001	.002	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,642 associations by consensus.

Dicarboxylic acid biosynthetic process by HAAO expression — LUNG_SCLC

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