H4C6

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, H4C6 RNA expression is significantly associated with the go_rna of many other GO terms, with 522 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H4C6-associated GO terms across cancer lineages are Nuclear body organization, Mammary gland alveolus development, and Mammary gland lobule development. Each is linked with H4C6 in more than 3 cancer types. Because this analysis shows association rather than direction, both H4C6-to-partner and partner-to-H4C6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear body organization grouped by H4C6-low versus H4C6-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C6→partner) and Y-score (partner→H4C6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaNuclear body organization →+0.049+0.254.005.00534
SKINMammary gland alveolus development →-0.132-0.136.008.00733
SKINMammary gland lobule development →-0.132-0.136.008.00733
SKINResponse to fungicide →-0.068-0.191.004.00932
BLOOD_LeukemiaCellular response to aldehyde →-0.080-0.344<.001.00132
BLOOD_LeukemiaGCN2-mediated signaling →-0.064-0.279.009.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 522 associations by consensus.

Nuclear body organization by H4C6 expression — BLOOD_Lymphoma

Box plot of Nuclear body organization in H4C6-low vs H4C6-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration