H4C14

Across TCGA cell cohorts, H4C14 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,913 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible H4C14-associated GO terms across cancer lineages are Vesicle budding from membrane, Positive regulation of signal transduction by p53 class mediator, and Regulation of response to endoplasmic reticulum stress. Each is linked with H4C14 in more than 8 cancer types. Because this analysis shows association rather than direction, both H4C14-to-partner and partner-to-H4C14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle budding from membrane grouped by H4C14-low versus H4C14-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C14→partner) and Y-score (partner→H4C14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Vesicle budding from membrane →	+0.074	+1.399	<.001	.005	3	9
UPPER_AERODIGESTIVE_TRACT	Positive regulation of signal transduction by p53 class mediator →	+0.082	+1.542	.005	<.001	3	9
PANCREAS	Regulation of response to endoplasmic reticulum stress →	+0.076	+1.263	.006	.007	3	9
STOMACH	Negative regulation of ubiquitin-dependent protein catabolic process →	+0.090	+1.649	.002	.002	3	9
LARGE_INTESTINE	Protein localization to CENP-A containing chromatin →	+0.186	+1.389	.002	<.001	2	9
LUNG_SCLC	Vesicle coating →	+0.081	+1.204	.008	.006	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,913 associations by consensus.

Vesicle budding from membrane by H4C14 expression — PANCREAS

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