H4C14

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, H4C14 protein abundance is significantly associated with the RNA expression of many other genes, with 3,570 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H4C14-associated genes across cancer lineages are RAB15, SP4, and ZFHX3. Each is linked with H4C14 in more than 5 cancer types. Because this analysis shows association rather than direction, both H4C14-to-partner and partner-to-H4C14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H4C14 versus RAB15 in LUNG_SCLC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C14→partner) and Y-score (partner→H4C14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCRAB15 →+1.331+0.841.001<.00136
BONESP4 →+1.354+1.459.001.00336
LUNG_SCLCZFHX3 →+0.889+0.760<.001<.00135
LUNG_SCLCWEE1 →+0.795+0.561<.001<.00135
LUNG_SCLCTINF2 →+0.906+0.716.001.00335
BLOOD_MyelomaBRICD5 →+1.887+0.716<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,570 associations by consensus.

H4C14 vs RAB15 — LUNG_SCLC

Per-sample scatter of H4C14 vs RAB15 in LUNG_SCLC (Pearson r = 0.51).

Explore this scatter interactively →

Exploration