H4C13

Across TCGA cell cohorts, H4C13 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,591 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H4C13-associated GO terms across cancer lineages are Negative regulation of B cell mediated immunity, Negative regulation of immunoglobulin mediated immune response, and Positive regulation of nuclear division. Each is linked with H4C13 in more than 5 cancer types. Because this analysis shows association rather than direction, both H4C13-to-partner and partner-to-H4C13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of B cell mediated immunity grouped by H4C13-low versus H4C13-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H4C13→partner) and Y-score (partner→H4C13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Negative regulation of B cell mediated immunity →	-0.175	-0.288	.001	.001	3	6
URINARY_TRACT	Negative regulation of immunoglobulin mediated immune response →	-0.175	-0.288	.001	.001	3	6
BLOOD_Leukemia	Positive regulation of nuclear division →	+0.071	+0.429	<.001	<.001	3	6
BLOOD_Lymphoma	Endosomal lumen acidification →	-0.070	-0.350	.003	.002	3	5
PANCREAS	Negative regulation of mitotic spindle assembly checkpoint signaling →	+0.127	+0.268	<.001	<.001	3	5
PANCREAS	Establishment of meiotic spindle orientation →	+0.100	+0.220	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,591 associations by consensus.

Negative regulation of B cell mediated immunity by H4C13 expression — URINARY_TRACT

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