Across TCGA patient cohorts, H4-16 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,593 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible H4-16-associated proteins across cancer lineages are SSR1, STX7, and TRAM1. Each is linked with H4-16 in more than 3 cancer types. Because this analysis shows association rather than direction, both H4-16-to-partner and partner-to-H4-16 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H4-16→partner) and Y-score (partner→H4-16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SSR1 →	-0.452	-0.781	.006	.002	3	4
HNSC	STX7 →	-0.301	-1.021	<.001	.001	3	4
UCEC	TRAM1 →	-0.522	-1.235	<.001	<.001	3	3
UCEC	CYBC1 →	-0.410	-0.880	.001	.003	3	3
LSCC	RFC5 →	+0.346	+0.439	<.001	.004	3	3
LSCC	SETDB1_S1066 →	+0.655	+0.645	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,593 associations by consensus.

Exploration

H4-16 survival (RNA) · tumor vs normal (RNA) · all H4-16 data types