H3Y1

Across TCGA patient cohorts, H3Y1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,437 significant associations in total. STAD shows the largest number of these associations.

The most reproducible H3Y1-associated GO terms across cancer lineages are Response to topologically incorrect protein, Osteoblast differentiation, and Regulation of mitochondrial fission. Each is linked with H3Y1 in more than 8 cancer types. Because this analysis shows association rather than direction, both H3Y1-to-partner and partner-to-H3Y1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to topologically incorrect protein grouped by H3Y1-low versus H3Y1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H3Y1→partner) and Y-score (partner→H3Y1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Response to topologically incorrect protein →	+0.100	+0.117	<.001	<.001	3	9
STAD	Osteoblast differentiation →	+0.066	+0.121	<.001	<.001	3	8
STAD	Regulation of mitochondrial fission →	+0.071	+0.130	<.001	<.001	3	8
STAD	Protein insertion into membrane →	+0.107	+0.111	<.001	<.001	3	8
STAD	Nucleoside triphosphate metabolic process →	+0.107	+0.121	<.001	<.001	3	8
STAD	Vesicle localization →	+0.080	+0.084	<.001	.006	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,437 associations by consensus.

Response to topologically incorrect protein by H3Y1 expression — STAD

Explore this box plot interactively →