H3P8

Across TCGA patient cohorts, H3P8 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,033 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible H3P8-associated proteins across cancer lineages are SIN3B, HDGFL3, and HDDC3. Each is linked with H3P8 in more than 3 cancer types. Because this analysis shows association rather than direction, both H3P8-to-partner and partner-to-H3P8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H3P8 versus SIN3B in GBM, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H3P8→partner) and Y-score (partner→H3P8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SIN3B →	+0.237	+0.658	<.001	<.001	3	4
GBM	HDGFL3 →	+0.432	+0.474	<.001	<.001	3	4
UCEC	HDDC3 →	-0.440	-1.152	<.001	<.001	3	3
CCRCC	ARVCF_T642 →	+0.713	+0.656	<.001	<.001	3	3
UCEC	SHTN1 →	-0.540	-0.940	<.001	<.001	3	3
PDAC	SVIL →	+0.276	+0.592	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,033 associations by consensus.

H3P8 vs SIN3B — GBM

Explore this scatter interactively →