H3P8

Across TCGA pan-cancer cohorts, H3P8 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of H3P8’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where H3P8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types H3P8 is over-expressed in tumor, although a few such as KIRP and KICH show the opposite, repressed pattern.

KIRC, KIRP, and BRCA are the cancer types where H3P8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in H3P8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.046	.011	5	view →
KIRP	Female	II,III,IV	−0.090	.042	2	view →
BRCA	All	All	+0.099	.046	1	view →
KICH	All	All	−0.071	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

H3P8–KIRC

Open the KIRC breakdown →