H3P39

Across TCGA patient cohorts, H3P39 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,526 significant associations in total. STAD shows the largest number of these associations.

The most reproducible H3P39-associated GO terms across cancer lineages are Mitochondrial gene expression, DNA-templated transcription initiation, and Protein monoubiquitination. Each is linked with H3P39 in more than 17 cancer types. Because this analysis shows association rather than direction, both H3P39-to-partner and partner-to-H3P39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by H3P39-low versus H3P39-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H3P39→partner) and Y-score (partner→H3P39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Mitochondrial gene expression →	+0.054	+0.224	.002	.001	3	17
ESCA	DNA-templated transcription initiation →	+0.057	+0.265	.001	<.001	3	17
THYM	Protein monoubiquitination →	+0.046	+0.361	<.001	<.001	3	17
ESCA	Regulation of double-strand break repair via homologous recombination →	+0.062	+0.322	.003	<.001	2	18
ESCA	Positive regulation of DNA-templated transcription initiation →	+0.043	+0.209	<.001	<.001	3	16
STAD	DNA-templated transcription elongation →	+0.049	+0.242	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,526 associations by consensus.

Mitochondrial gene expression by H3P39 expression — ESCA

Explore this box plot interactively →