H3P38

Across TCGA patient cohorts, H3P38 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,441 significant associations in total. STAD shows the largest number of these associations.

The most reproducible H3P38-associated GO terms across cancer lineages are Cellular response to oxidative stress, Cellular response to topologically incorrect protein, and Negative regulation of cellular catabolic process. Each is linked with H3P38 in more than 16 cancer types. Because this analysis shows association rather than direction, both H3P38-to-partner and partner-to-H3P38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to oxidative stress grouped by H3P38-low versus H3P38-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H3P38→partner) and Y-score (partner→H3P38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Cellular response to oxidative stress →	+0.055	+0.271	<.001	<.001	3	17
STAD	Cellular response to topologically incorrect protein →	+0.063	+0.282	<.001	<.001	3	17
STAD	Negative regulation of cellular catabolic process →	+0.055	+0.315	<.001	<.001	3	17
STAD	Protein modification by small protein removal →	+0.062	+0.289	<.001	<.001	3	17
STAD	Regulation of DNA repair →	+0.055	+0.263	<.001	<.001	3	17
STAD	tRNA modification →	+0.050	+0.292	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,441 associations by consensus.

Cellular response to oxidative stress by H3P38 expression — STAD

Explore this box plot interactively →