H3P34

Across TCGA pan-cancer cohorts, H3P34 RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated H3P34 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher H3P34 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated H3P34 expression acts as an unfavorable survival marker, although some lineages such as SKCM and KICH show a favorable association.

BLCA, HNSC, and SKCM are the cancer types where H3P34 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.128	0.631	<.001	144	view →
HNSC	OS	Tertile	II,III,IV	0.331	0.654	.008	81	view →
SKCM	DFS	Tertile	All	0.291	0.160	<.001	37	view →
UCEC	DFS	Tertile	All	0.425	0.657	.038	12	view →
KICH	OS	Tertile	II,III,IV	1.000	0.521	.031	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

H3P34–BLCA (DFS)

Open the BLCA breakdown →