H3P3

Across TCGA patient cohorts, H3P3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,461 significant associations in total. STAD shows the largest number of these associations.

The most reproducible H3P3-associated GO terms across cancer lineages are Mitochondrial RNA metabolic process, Regulation of transcription elongation by RNA polymerase II, and Ribosomal small subunit biogenesis. Each is linked with H3P3 in more than 11 cancer types. Because this analysis shows association rather than direction, both H3P3-to-partner and partner-to-H3P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial RNA metabolic process grouped by H3P3-low versus H3P3-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H3P3→partner) and Y-score (partner→H3P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Mitochondrial RNA metabolic process →	+0.064	+0.487	<.001	<.001	3	12
STAD	Regulation of transcription elongation by RNA polymerase II →	+0.064	+0.507	<.001	<.001	3	12
STAD	Ribosomal small subunit biogenesis →	+0.068	+0.476	<.001	<.001	3	12
ESCA	Protein-RNA complex organization →	+0.069	+0.523	<.001	<.001	3	12
ESCA	tRNA metabolic process →	+0.059	+0.494	<.001	<.001	3	11
ESCA	Positive regulation of post-translational protein modification →	+0.059	+0.469	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,461 associations by consensus.

Mitochondrial RNA metabolic process by H3P3 expression — ESCA

Explore this box plot interactively →