H3P25

Across TCGA patient cohorts, H3P25 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,458 significant associations in total. GBM shows the largest number of these associations.

The most reproducible H3P25-associated proteins across cancer lineages are EIF4G2, HTATIP2, and PPWD1. Each is linked with H3P25 in more than 2 cancer types. Because this analysis shows association rather than direction, both H3P25-to-partner and partner-to-H3P25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H3P25 versus EIF4G2 in BRCA, with a Pearson correlation of -0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H3P25→partner) and Y-score (partner→H3P25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EIF4G2 →	-0.185	-0.475	.003	<.001	3	3
GBM	HTATIP2 →	-0.591	-0.383	<.001	.006	3	3
GBM	PPWD1 →	+0.214	+0.379	.004	.003	3	3
GBM	PHAX →	+0.250	+0.397	.001	<.001	3	3
PDAC	XPC_S884 →	+1.075	+0.531	<.001	.003	3	2
HNSC	ZDHHC5_S636 →	-0.636	-0.857	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,458 associations by consensus.

H3P25 vs EIF4G2 — BRCA

Explore this scatter interactively →