H3P24

Across TCGA patient cohorts, H3P24 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,070 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible H3P24-associated GO terms across cancer lineages are U2-type prespliceosome assembly, Ribosomal large subunit assembly, and Telomere maintenance. Each is linked with H3P24 in more than 14 cancer types. Because this analysis shows association rather than direction, both H3P24-to-partner and partner-to-H3P24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, U2-type prespliceosome assembly grouped by H3P24-low versus H3P24-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H3P24→partner) and Y-score (partner→H3P24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	U2-type prespliceosome assembly →	+0.051	+0.199	<.001	.001	3	15
ESCA	Ribosomal large subunit assembly →	+0.045	+0.248	<.001	<.001	3	14
ESCA	Telomere maintenance →	+0.062	+0.378	.009	<.001	3	14
THYM	DNA strand elongation →	+0.038	+0.248	<.001	<.001	3	13
ESCA	Methylation →	+0.032	+0.186	.001	.003	3	13
ESCA	Macromolecule methylation →	+0.034	+0.231	.002	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,070 associations by consensus.

U2-type prespliceosome assembly by H3P24 expression — ESCA

Explore this box plot interactively →