H3P24

Across TCGA pan-cancer cohorts, H3P24 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated H3P24 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher H3P24 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated H3P24 expression acts as an unfavorable survival marker, although some lineages such as UCEC and ACC show a favorable association.

KICH, UCEC, and STAD are the cancer types where H3P24 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Quartile	All	0.810	1.000	<.001	81	view →
UCEC	OS	Quartile	IV	0.854	0.406	.001	62	view →
STAD	DFS	Quartile	II,III,IV	0.358	0.754	.018	28	view →
MESO	DFS	Tertile	II,III,IV	0.225	0.540	.010	27	view →
ACC	OS	Median	III,IV	0.939	0.569	.002	27	view →
LUAD	OS	Tertile	All	0.750	0.884	.002	26	view →
CESC	OS	Quartile	II,III,IV	0.931	0.718	.010	24	view →
LUSC	OS	Median	II,III,IV	0.484	0.309	.011	22	view →
READ	OS	Tertile	II,III,IV	0.638	1.000	.006	22	view →
ESCA	DFS	Tertile	All	0.452	0.641	.009	17	view →
LIHC	OS	Quartile	II,III,IV	0.535	0.764	.005	10	view →
SKCM	DFS	Quartile	IV	0.943	0.172	.018	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

H3P24–KICH (OS)

Open the KICH breakdown →