H3P23

Across TCGA patient cohorts, H3P23 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,008 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible H3P23-associated GO terms across cancer lineages are Regulation of double-strand break repair via homologous recombination, Microtubule polymerization, and Regulation of nucleotide-excision repair. Each is linked with H3P23 in more than 16 cancer types. Because this analysis shows association rather than direction, both H3P23-to-partner and partner-to-H3P23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair via homologous recombination grouped by H3P23-low versus H3P23-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H3P23→partner) and Y-score (partner→H3P23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of double-strand break repair via homologous recombination →	+0.036	+0.203	<.001	<.001	3	16
STAD	Microtubule polymerization →	+0.049	+0.327	<.001	<.001	2	17
ESCA	Regulation of nucleotide-excision repair →	+0.069	+0.394	.001	<.001	3	15
STAD	Regulatory ncRNA processing →	+0.043	+0.331	<.001	<.001	3	15
STAD	Regulation of double-strand break repair →	+0.036	+0.210	<.001	<.001	3	15
THYM	DNA-templated transcription initiation →	+0.044	+0.220	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,008 associations by consensus.

Regulation of double-strand break repair via homologous recombination by H3P23 expression — STAD

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