H3P22

Across TCGA patient cohorts, H3P22 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,097 significant associations in total. STAD shows the largest number of these associations.

The most reproducible H3P22-associated GO terms across cancer lineages are Positive regulation of growth, Regulation of mitochondrion organization, and Positive regulation of transmembrane transport. Each is linked with H3P22 in more than 8 cancer types. Because this analysis shows association rather than direction, both H3P22-to-partner and partner-to-H3P22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of growth grouped by H3P22-low versus H3P22-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H3P22→partner) and Y-score (partner→H3P22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of growth →	+0.074	+0.083	<.001	<.001	3	9
STAD	Regulation of mitochondrion organization →	+0.106	+0.086	<.001	<.001	3	8
STAD	Positive regulation of transmembrane transport →	+0.056	+0.101	<.001	<.001	3	8
STAD	Positive regulation of monoatomic ion transport →	+0.047	+0.091	<.001	<.001	3	8
ESCA	Mitochondrial transport →	+0.136	+0.084	<.001	.005	2	8
ESCA	Regulation of protein serine/threonine kinase activity →	+0.110	+0.115	<.001	.006	1	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,097 associations by consensus.

Positive regulation of growth by H3P22 expression — STAD

Explore this box plot interactively →