H3P20

Across TCGA patient cohorts, H3P20 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,010 significant associations in total. STAD shows the largest number of these associations.

The most reproducible H3P20-associated GO terms across cancer lineages are Mitochondrial membrane organization, Positive regulation of mitotic cell cycle spindle assembly checkpoint, and Regulation of double-strand break repair via homologous recombination. Each is linked with H3P20 in more than 6 cancer types. Because this analysis shows association rather than direction, both H3P20-to-partner and partner-to-H3P20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial membrane organization grouped by H3P20-low versus H3P20-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H3P20→partner) and Y-score (partner→H3P20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial membrane organization →	+0.132	+0.056	<.001	<.001	3	7
STAD	Positive regulation of mitotic cell cycle spindle assembly checkpoint →	+0.107	+0.057	<.001	<.001	3	6
STAD	Regulation of double-strand break repair via homologous recombination →	+0.124	+0.063	<.001	<.001	3	6
STAD	Nucleobase-containing compound transport →	+0.133	+0.065	<.001	<.001	3	6
STAD	mRNA 3'-end processing →	+0.126	+0.061	<.001	<.001	3	6
STAD	Positive regulation of transcription elongation by RNA polymerase II →	+0.135	+0.066	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,010 associations by consensus.

Mitochondrial membrane organization by H3P20 expression — STAD

Explore this box plot interactively →