H3P20

Across TCGA pan-cancer cohorts, H3P20 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated H3P20 data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher H3P20 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated H3P20 expression acts as an unfavorable survival marker.

TGCT, KIRC, and OV are the cancer types where H3P20 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	OS	Tertile	All	0.508	0.991	<.001	90	view →
KIRC	OS	Tertile	All	0.658	0.811	.013	48	view →
OV	OS	Tertile	IV	0.028	0.759	.002	36	view →
LAML	DFS	Tertile	All	0.152	0.578	.016	36	view →
STAD	DFS	Tertile	III,IV	0.186	0.613	.001	27	view →
THCA	DFS	Tertile	All	0.184	0.814	.023	9	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

H3P20–TGCT (OS)

Open the TGCT breakdown →