H3P11

Across TCGA pan-cancer cohorts, H3P11 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated H3P11 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher H3P11 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated H3P11 expression acts as an unfavorable survival marker.

UVM, LUSC, and LUAD are the cancer types where H3P11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.104	0.834	<.001	63	view →
LUSC	DFS	Tertile	II,III,IV	0.159	0.683	.001	60	view →
LUAD	OS	Tertile	II,III,IV	0.153	0.750	<.001	36	view →
UCS	DFS	Tertile	All	0.136	0.523	.034	18	view →
THCA	OS	Tertile	III,IV	0.598	0.888	.006	12	view →
PAAD	DFS	Tertile	All	0.115	0.504	.034	9	view →
COAD	DFS	Tertile	IV	0.035	0.501	<.001	9	view →
PCPG	OS	Tertile	All	0.834	0.974	.045	9	view →
PRAD	OS	Tertile	All	0.591	0.924	.019	6	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

H3P11–UVM (OS)

Open the UVM breakdown →