H3P11

Across TCGA pan-cancer cohorts, H3P11 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of H3P11’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where H3P11 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types H3P11 is over-expressed in tumor.

LUSC are the cancer types where H3P11 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in H3P11 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.025	.020	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

H3P11–LUSC

Open the LUSC breakdown →