H3C8

Across TCGA patient cohorts, H3C8 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,469 significant associations in total. GBM shows the largest number of these associations.

The most reproducible H3C8-associated proteins across cancer lineages are RFC1_T506, CDC20_T70, and CDK1. Each is linked with H3C8 in more than 5 cancer types. Because this analysis shows association rather than direction, both H3C8-to-partner and partner-to-H3C8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H3C8 versus RFC1_T506 in CCRCC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H3C8→partner) and Y-score (partner→H3C8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RFC1_T506 →	+0.956	+1.118	<.001	<.001	3	6
GBM	CDC20_T70 →	+1.449	+2.385	<.001	<.001	3	6
CCRCC	CDK1 →	+0.708	+0.845	<.001	<.001	3	6
LSCC	RBBP5_S497 →	+0.679	+1.141	.004	.007	3	6
GBM	TTK_S436 →	+1.037	+2.656	<.001	<.001	3	5
LSCC	UBTF_S484 →	+0.933	+1.109	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,469 associations by consensus.

H3C8 vs RFC1_T506 — CCRCC

Explore this scatter interactively →