H3C2

Across TCGA patient cohorts, H3C2 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,899 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H3C2-associated proteins across cancer lineages are RRM2, ANLN, and CDC20_T70. Each is linked with H3C2 in more than 8 cancer types. Because this analysis shows association rather than direction, both H3C2-to-partner and partner-to-H3C2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H3C2 versus RRM2 in LUAD, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H3C2→partner) and Y-score (partner→H3C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RRM2 →	+1.022	+1.440	<.001	<.001	3	9
LUAD	ANLN →	+1.175	+1.447	<.001	<.001	3	9
LUAD	CDC20_T70 →	+1.392	+1.465	<.001	<.001	3	9
GBM	SMC2 →	+0.753	+1.797	<.001	<.001	3	8
LUAD	SMC4 →	+0.734	+1.451	<.001	<.001	3	8
LUAD	NCAPD2 →	+0.829	+1.431	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,899 associations by consensus.

H3C2 vs RRM2 — LUAD

Explore this scatter interactively →