H3C10

Across TCGA patient cohorts, H3C10 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,408 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H3C10-associated proteins across cancer lineages are SMC4, RBBP5_S497, and BAZ1A. Each is linked with H3C10 in more than 7 cancer types. Because this analysis shows association rather than direction, both H3C10-to-partner and partner-to-H3C10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H3C10 versus SMC4 in GBM, with a Pearson correlation of 0.72.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H3C10→partner) and Y-score (partner→H3C10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SMC4 →	+0.714	+1.261	<.001	<.001	3	8
LUAD	RBBP5_S497 →	+1.090	+0.986	<.001	<.001	3	7
LSCC	BAZ1A →	+0.354	+0.745	<.001	<.001	3	7
LUAD	CDK1 →	+0.962	+1.115	<.001	<.001	3	7
GBM	DNMT1 →	+0.483	+1.141	<.001	<.001	3	7
LUAD	FANCD2_S1435 →	+1.022	+1.105	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,408 associations by consensus.

H3C10 vs SMC4 — GBM

Explore this scatter interactively →