Across TCGA cell cohorts, H3-5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,102 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H3-5-associated GO terms across cancer lineages are Regulation of Golgi inheritance, Response to dehydroepiandrosterone, and Positive regulation of RNA polymerase II transcription preinitiation complex assembly. Each is linked with H3-5 in more than 13 cancer types. Because this analysis shows association rather than direction, both H3-5-to-partner and partner-to-H3-5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H3-5→partner) and Y-score (partner→H3-5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of Golgi inheritance →	+0.182	+0.807	<.001	.004	3	14
SOFT_TISSUE	Response to dehydroepiandrosterone →	+0.192	+0.408	<.001	.001	3	13
BLOOD_Leukemia	Positive regulation of RNA polymerase II transcription preinitiation complex assembly →	+0.160	+0.462	<.001	<.001	3	12
BONE	Negative regulation of mRNA splicing, via spliceosome →	+0.087	+0.553	.002	.001	3	12
BONE	Negative regulation of mRNA processing →	+0.082	+0.553	.003	.001	3	12
BONE	Negative regulation of RNA splicing →	+0.097	+0.571	.003	.005	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,102 associations by consensus.

Exploration

H3-5 survival (RNA) · tumor vs normal (RNA) · all H3-5 data types