H3-2

Across TCGA patient cohorts, H3-2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,247 significant associations in total. GBM shows the largest number of these associations.

The most reproducible H3-2-associated proteins across cancer lineages are ITGA5, MRPL40, and P3H3. Each is linked with H3-2 in more than 3 cancer types. Because this analysis shows association rather than direction, both H3-2-to-partner and partner-to-H3-2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H3-2 versus ITGA5 in LSCC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H3-2→partner) and Y-score (partner→H3-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ITGA5 →	+0.551	+0.495	<.001	.003	3	4
LSCC	MRPL40 →	-0.380	-0.371	<.001	<.001	3	4
OV	P3H3 →	+0.602	+0.508	<.001	<.001	3	4
BRCA	P4HA2 →	+0.716	+0.282	<.001	.005	3	4
OV	FN1 →	+0.951	+0.505	<.001	.002	3	4
OV	ITGAV →	+0.525	+0.424	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,247 associations by consensus.

H3-2 vs ITGA5 — LSCC

Explore this scatter interactively →