H3-2

Across TCGA patient cohorts, H3-2 protein abundance is significantly associated with the protein abundance of many other proteins, with 13,501 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible H3-2-associated proteins across cancer lineages are ZNF512, H1-5, and S100A12. Each is linked with H3-2 in more than 4 cancer types. Because this analysis shows association rather than direction, both H3-2-to-partner and partner-to-H3-2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H3-2 versus ZNF512 in UCEC, with a Pearson correlation of 0.74.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H3-2→partner) and Y-score (partner→H3-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF512 →	+0.915	+1.308	<.001	<.001	3	5
LUAD	H1-5 →	+1.136	+0.863	<.001	<.001	3	4
LUAD	S100A12 →	+1.484	+0.926	<.001	<.001	2	5
LUAD	MPO →	+1.231	+0.926	<.001	<.001	3	4
UCEC	NCL →	-0.479	-1.499	<.001	.001	3	4
BRCA	ANXA1 →	+0.718	+1.032	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,501 associations by consensus.

H3-2 vs ZNF512 — UCEC

Explore this scatter interactively →