H2BW1

Across TCGA cell cohorts, H2BW1 RNA expression is significantly associated with the go_rna of many other GO terms, with 386 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible H2BW1-associated GO terms across cancer lineages are Response to type I interferon, mRNA catabolic process, and Ethanolamine transport. Each is linked with H2BW1 in more than 4 cancer types. Because this analysis shows association rather than direction, both H2BW1-to-partner and partner-to-H2BW1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to type I interferon grouped by H2BW1-low versus H2BW1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BW1→partner) and Y-score (partner→H2BW1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Response to type I interferon →	+0.104	+0.046	<.001	.002	3	5
UPPER_AERODIGESTIVE_TRACT	mRNA catabolic process →	+0.043	+0.087	<.001	.001	3	4
LUNG_NSCLC_LUSC	Ethanolamine transport →	+0.140	+0.188	.006	.002	3	3
URINARY_TRACT	Response to indole-3-methanol →	+0.146	+0.030	.008	.006	3	3
UPPER_AERODIGESTIVE_TRACT	Negative regulation of DNA-templated transcription, elongation →	+0.082	+0.085	<.001	.002	3	3
UPPER_AERODIGESTIVE_TRACT	Vesicle targeting, to, from or within Golgi →	+0.072	+0.106	.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 386 associations by consensus.

Response to type I interferon by H2BW1 expression — URINARY_TRACT

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