H2BC9

Across TCGA cell cohorts, H2BC9 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,736 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H2BC9-associated GO terms across cancer lineages are Negative regulation of ubiquitin-dependent protein catabolic process, Innate immune response in mucosa, and Mucosal immune response. Each is linked with H2BC9 in more than 7 cancer types. Because this analysis shows association rather than direction, both H2BC9-to-partner and partner-to-H2BC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of ubiquitin-dependent protein catabolic process grouped by H2BC9-low versus H2BC9-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC9→partner) and Y-score (partner→H2BC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of ubiquitin-dependent protein catabolic process →	+0.058	+0.894	.006	<.001	3	7
LUNG_SCLC	Innate immune response in mucosa →	-0.154	-1.363	.007	<.001	2	8
LUNG_SCLC	Mucosal immune response →	-0.173	-1.464	<.001	<.001	3	7
LUNG_SCLC	Transcription elongation-coupled chromatin remodeling →	+0.104	+1.171	<.001	<.001	3	6
OVARY	Macroautophagy →	+0.041	+0.803	.006	.002	3	6
OVARY	Regulation of proteasomal protein catabolic process →	+0.059	+0.867	.003	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,736 associations by consensus.

Negative regulation of ubiquitin-dependent protein catabolic process by H2BC9 expression — OVARY

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