H2BC8

Across TCGA patient cohorts, H2BC8 mutation is significantly associated with the RNA expression of many other genes, with 149 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible H2BC8-associated genes across cancer lineages are RN7SL419P, RNU5E-9P, and RN7SL530P. Each is linked with H2BC8 in more than 2 cancer types. Because this analysis shows association rather than direction, both H2BC8-to-partner and partner-to-H2BC8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL419P grouped by H2BC8-low versus H2BC8-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC8→partner) and Y-score (partner→H2BC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SL419P →	+0.239	+5.602	.007	<.001	3	3
HNSC	RNU5E-9P →	+0.376	+6.623	<.001	<.001	3	2
COAD	RN7SL530P →	+1.473	+4.993	<.001	.002	3	2
UCEC	RNA5SP241 →	+0.733	+3.657	<.001	<.001	3	2
UCEC	SUMO2P13 →	+0.217	+2.545	.007	.006	3	2
LUSC	FCF1P10 →	+0.116	+3.956	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 149 associations by consensus.

RN7SL419P by H2BC8 expression — COAD

Explore this box plot interactively →