H2BC8

Across TCGA cell cohorts, H2BC8 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,918 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H2BC8-associated GO terms across cancer lineages are COPII-coated vesicle budding, Regulation of RNA splicing, and Autophagy of mitochondrion. Each is linked with H2BC8 in more than 7 cancer types. Because this analysis shows association rather than direction, both H2BC8-to-partner and partner-to-H2BC8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII-coated vesicle budding grouped by H2BC8-low versus H2BC8-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC8→partner) and Y-score (partner→H2BC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	COPII-coated vesicle budding →	+0.067	+1.216	.001	.004	3	8
OVARY	Regulation of RNA splicing →	+0.064	+1.228	<.001	.001	3	8
LARGE_INTESTINE	Autophagy of mitochondrion →	+0.050	+0.942	.005	.003	3	7
LARGE_INTESTINE	Epidermal growth factor receptor signaling pathway →	+0.055	+1.074	.003	.006	3	7
LARGE_INTESTINE	Response to unfolded protein →	+0.054	+0.930	<.001	<.001	3	7
LIVER	Post-transcriptional gene silencing →	+0.071	+0.911	.007	.006	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,918 associations by consensus.

COPII-coated vesicle budding by H2BC8 expression — OVARY

Explore this box plot interactively →