H2BC5

Across TCGA patient cohorts, H2BC5 mutation is significantly associated with the RNA expression of many other genes, with 257 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible H2BC5-associated genes across cancer lineages are GUSBP15, GLYCAM1, and PRELID3BP8. Each is linked with H2BC5 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2BC5-to-partner and partner-to-H2BC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GUSBP15 grouped by H2BC5-low versus H2BC5-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC5→partner) and Y-score (partner→H2BC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GUSBP15 →	+0.146	+4.399	<.001	.006	3	2
BLCA	GLYCAM1 →	+0.024	+4.233	<.001	.006	3	2
BLCA	PRELID3BP8 →	+0.170	+3.588	<.001	.003	3	2
LUAD	RNU1-89P →	+1.559	+5.584	<.001	.002	3	2
LUAD	RNU6-75P →	+0.411	+5.912	<.001	.001	3	2
LUAD	LINC01581 →	+0.072	+4.345	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 257 associations by consensus.

GUSBP15 by H2BC5 expression — COAD

Explore this box plot interactively →