H2BC3

Across TCGA patient cohorts, H2BC3 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible H2BC3-associated genes across cancer lineages are CD4+ memory T-cells, Class-switched memory B-cells, and lymphatic Endothelial cells. Each is linked with H2BC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2BC3-to-partner and partner-to-H2BC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ memory T-cells grouped by H2BC3-low versus H2BC3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC3→partner) and Y-score (partner→H2BC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CD4+ memory T-cells →	+0.022	+3.958	.029	.035	3	1
UCEC	Class-switched memory B-cells →	-0.059	-3.321	.048	.010	2	1
UCEC	lymphatic Endothelial cells →	-0.029	-3.129	.019	.019	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD4+ memory T-cells by H2BC3 expression — COAD

Explore this box plot interactively →