H2BC2P

Across TCGA pan-cancer cohorts, H2BC2P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated H2BC2P data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher H2BC2P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated H2BC2P expression acts as an unfavorable survival marker, although some lineages such as OV and CHOL show a favorable association.

UCS, ACC, and STAD are the cancer types where H2BC2P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	All	0.135	0.687	.009	72	view →
ACC	DFS	Tertile	All	0.068	0.667	.005	36	view →
STAD	OS	Tertile	IV	0.052	0.541	.003	27	view →
BLCA	DFS	Tertile	All	0.127	0.594	.020	24	view →
LAML	DFS	Tertile	All	0.186	0.596	.016	18	view →
COAD	OS	Tertile	III,IV	0.163	0.791	.004	18	view →
SKCM	OS	Tertile	III,IV	0.179	0.721	<.001	9	view →
KIRP	DFS	Quartile	All	0.493	0.682	.016	8	view →
OV	DFS	Tertile	III,IV	0.257	0.145	.038	6	view →
LGG	OS	Tertile	All	0.170	0.523	.029	6	view →
CHOL	OS	Tertile	All	1.000	0.384	.039	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

H2BC2P–UCS (OS)

Open the UCS breakdown →