Across TCGA patient cohorts, H2BC21 mutation is significantly associated with the RNA expression of many other genes, with 175 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible H2BC21-associated genes across cancer lineages are MIR548C, CDY10P, and RNU6-40P. Each is linked with H2BC21 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2BC21-to-partner and partner-to-H2BC21 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC21→partner) and Y-score (partner→H2BC21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR548C →	+0.350	+5.124	.003	.008	3	2
SKCM	CDY10P →	+0.046	+5.624	<.001	.002	3	2
CESC	RNU6-40P →	+0.119	+3.984	<.001	.009	3	2
CESC	OR7E104P →	+0.014	+2.918	<.001	.007	3	2
LUSC	RNU6-173P →	+0.788	+4.067	<.001	.005	3	2
LUSC	CA15P2 →	+0.038	+4.297	.004	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 175 associations by consensus.

Exploration

H2BC21 survival (RNA) · tumor vs normal (RNA) · all H2BC21 data types