H2BC18

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, H2BC18 mutation is significantly associated with the RNA expression of many other genes, with 114 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible H2BC18-associated genes across cancer lineages are MED28P6, ZNF519P4, and RNU6-806P. Each is linked with H2BC18 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2BC18-to-partner and partner-to-H2BC18 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC18→partner) and Y-score (partner→H2BC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAMED28P6 →+0.174+7.640<.001.00932
UCECZNF519P4 →+0.479+3.562<.001.00432
LUSCRNU6-806P →+0.544+5.081<.001<.00132
UCECRNA5SP222 →+0.232+4.292<.001.00632
SKCMOR7E18P →+0.044+4.513<.001.00932
BLCAOR4A48P →+0.068+7.640<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 114 associations by consensus.

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