Across TCGA cell cohorts, H2BC18 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible H2BC18-associated genes across cancer lineages are OR11H6, KRTAP9-8, and FCN2. Each is linked with H2BC18 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2BC18-to-partner and partner-to-H2BC18 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC18→partner) and Y-score (partner→H2BC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR11H6 →	+0.024	+5.794	<.001	<.001	3	1
BLOOD_Lymphoma	KRTAP9-8 →	+0.022	+5.247	<.001	.001	3	1
LARGE_INTESTINE	FCN2 →	+0.024	+5.415	.007	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

H2BC18 survival (RNA) · tumor vs normal (RNA) · all H2BC18 data types