H2BC1

Across TCGA patient cohorts, H2BC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,995 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible H2BC1-associated proteins across cancer lineages are ZFHX3_S2795, RBBP6_S772, and MEMO1. Each is linked with H2BC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both H2BC1-to-partner and partner-to-H2BC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H2BC1 versus ZFHX3_S2795 in HNSC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC1→partner) and Y-score (partner→H2BC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZFHX3_S2795 →	+0.292	+0.403	.006	.006	3	3
PDAC	RBBP6_S772 →	-0.794	-0.273	<.001	<.001	3	2
PDAC	MEMO1 →	-0.319	-0.362	<.001	<.001	3	2
PDAC	MTMR12 →	+0.171	+0.280	<.001	.003	3	2
PDAC	MYOF_S731 →	-0.598	-0.370	<.001	<.001	3	2
LUAD	NELFB →	+0.184	+1.052	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,995 associations by consensus.

H2BC1 vs ZFHX3_S2795 — HNSC

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