H2BC1

Across TCGA cell cohorts, H2BC1 RNA expression is significantly associated with the mutation status of many other genes, with 157 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible H2BC1-associated genes across cancer lineages are CLSTN2, SEMA5A, and PDZD8. Each is linked with H2BC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2BC1-to-partner and partner-to-H2BC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLSTN2 grouped by H2BC1-low versus H2BC1-high in SOFT_TISSUE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC1→partner) and Y-score (partner→H2BC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CLSTN2 →	+4.392	+0.260	.004	<.001	3	2
UPPER_AERODIGESTIVE_TRACT	SEMA5A →	+4.357	+0.032	.006	<.001	3	2
LUNG_NSCLC_LUSC	PDZD8 →	+4.643	+0.046	.008	<.001	3	1
SOFT_TISSUE	DNAJC5 →	+5.977	+0.433	.001	<.001	3	1
SOFT_TISSUE	SLC17A9 →	+4.977	+0.325	.002	<.001	3	1
SOFT_TISSUE	ZNF423 →	+3.977	+0.216	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 157 associations by consensus.

CLSTN2 by H2BC1 expression — SOFT_TISSUE

Explore this box plot interactively →