H2AZP5

Across TCGA pan-cancer cohorts, H2AZP5 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated H2AZP5 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher H2AZP5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated H2AZP5 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

UVM, MESO, and BLCA are the cancer types where H2AZP5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.075	0.858	<.001	108	view →
MESO	DFS	Tertile	II,III,IV	0.122	0.418	<.001	90	view →
BLCA	DFS	Tertile	IV	0.268	0.484	.014	54	view →
THYM	OS	Tertile	III,IV	0.615	1.000	.019	36	view →
CESC	DFS	Tertile	II,III,IV	0.603	0.813	.009	24	view →
ESCA	OS	Quartile	All	0.524	0.741	.009	13	view →
CHOL	OS	Tertile	All	0.154	0.793	.004	9	view →
ACC	DFS	Tertile	All	0.110	0.472	.033	6	view →
LUAD	OS	Tertile	All	0.658	0.275	.023	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

H2AZP5–UVM (OS)

Open the UVM breakdown →