H2AZ2

Across TCGA patient cohorts, H2AZ2 protein abundance is significantly associated with the RNA expression of many other genes, with 941 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H2AZ2-associated genes across cancer lineages are EPCAM, NR2C1, and H1-3. Each is linked with H2AZ2 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2AZ2-to-partner and partner-to-H2AZ2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H2AZ2 versus EPCAM in BRCA, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AZ2→partner) and Y-score (partner→H2AZ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EPCAM →	-0.889	-0.794	.008	.003	3	1
BRCA	NR2C1 →	+0.590	+0.928	.007	.009	3	1
BRCA	H1-3 →	-1.483	-0.705	.002	.006	3	1
BRCA	FAM155B →	-0.852	-0.833	.005	.006	3	1
BRCA	CUZD1 →	+0.142	+0.815	.003	.002	3	1
BRCA	ATP6V1G3 →	+0.155	+0.929	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 941 associations by consensus.

H2AZ2 vs EPCAM — BRCA

Explore this scatter interactively →