H2AZ2

Across TCGA cell cohorts, H2AZ2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,265 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H2AZ2-associated GO terms across cancer lineages are Positive regulation of cell cycle phase transition, Positive regulation of mitotic cell cycle phase transition, and Regulation of sister chromatid segregation. Each is linked with H2AZ2 in more than 16 cancer types. Because this analysis shows association rather than direction, both H2AZ2-to-partner and partner-to-H2AZ2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell cycle phase transition grouped by H2AZ2-low versus H2AZ2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AZ2→partner) and Y-score (partner→H2AZ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of cell cycle phase transition →	+0.092	+0.800	.001	<.001	3	17
BONE	Positive regulation of mitotic cell cycle phase transition →	+0.114	+0.802	.003	.009	3	17
OESOPHAGUS	Regulation of sister chromatid segregation →	+0.134	+0.908	<.001	<.001	3	17
OESOPHAGUS	Regulation of chromosome segregation →	+0.142	+0.988	<.001	<.001	3	17
OESOPHAGUS	Regulation of mitotic sister chromatid separation →	+0.169	+0.808	.001	<.001	2	17
KIDNEY	Positive regulation of mitotic sister chromatid separation →	+0.157	+0.632	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,265 associations by consensus.

Positive regulation of cell cycle phase transition by H2AZ2 expression — PANCREAS

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