H2AW

Across TCGA pan-cancer cohorts, H2AW Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated H2AW data layer compared with 24 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher H2AW Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated H2AW expression acts as an unfavorable survival marker.

LIHC, BLCA, and THYM are the cancer types where H2AW Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.128	0.783	.001	36	view →
BLCA	DFS	Median	All	0.242	0.628	.007	18	view →
THYM	OS	Median	All	0.186	0.931	<.001	15	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

H2AW–LIHC (OS)

Open the LIHC breakdown →