H2AW

Across TCGA patient cohorts, H2AW RNA expression is significantly associated with the protein abundance of many other proteins, with 10,013 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H2AW-associated proteins across cancer lineages are KDM1A, TMPO, and UBTF_S484. Each is linked with H2AW in more than 3 cancer types. Because this analysis shows association rather than direction, both H2AW-to-partner and partner-to-H2AW results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H2AW versus KDM1A in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AW→partner) and Y-score (partner→H2AW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KDM1A →	+0.269	+0.785	<.001	.004	3	4
LSCC	TMPO →	+0.369	+1.349	.001	<.001	3	4
LSCC	UBTF_S484 →	+1.100	+1.213	<.001	.001	3	4
GBM	UTP20_T1741 →	+0.353	+1.073	<.001	<.001	3	4
LUAD	YME1L1 →	+0.270	+1.221	<.001	<.001	3	4
LUAD	NAA10_S186 →	+0.461	+1.073	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,013 associations by consensus.

H2AW vs KDM1A — GBM

Explore this scatter interactively →