H2AC8

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, H2AC8 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. STAD shows the largest number of these associations.

The most reproducible H2AC8-associated genes across cancer lineages are NK cells. Each is linked with H2AC8 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2AC8-to-partner and partner-to-H2AC8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NK cells grouped by H2AC8-low versus H2AC8-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC8→partner) and Y-score (partner→H2AC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADNK cells →+0.009+5.597<.001.04031
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

NK cells by H2AC8 expression — STAD

Box plot of NK cells in H2AC8-low vs H2AC8-high samples in STAD.

Explore this box plot interactively →

Exploration