H2AC8

Across TCGA cell cohorts, H2AC8 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,241 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H2AC8-associated GO terms across cancer lineages are Autophagy of mitochondrion, Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, and Polysaccharide biosynthetic process. Each is linked with H2AC8 in more than 5 cancer types. Because this analysis shows association rather than direction, both H2AC8-to-partner and partner-to-H2AC8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagy of mitochondrion grouped by H2AC8-low versus H2AC8-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC8→partner) and Y-score (partner→H2AC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Autophagy of mitochondrion →	+0.051	+1.046	<.001	<.001	3	6
OVARY	Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.088	+0.926	.003	.006	3	5
OVARY	Polysaccharide biosynthetic process →	-0.115	-1.054	.002	<.001	3	5
OVARY	Positive regulation of TOR signaling →	+0.056	+1.084	.003	.003	3	5
BLOOD_Leukemia	Protein localization to CENP-A containing chromatin →	+0.210	+1.005	.007	<.001	3	5
CNS	Positive regulation of calcineurin-NFAT signaling cascade →	-0.096	-0.769	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,241 associations by consensus.

Autophagy of mitochondrion by H2AC8 expression — BLOOD_Leukemia

Explore this box plot interactively →