H2AC6

Across TCGA cell cohorts, H2AC6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,548 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible H2AC6-associated GO terms across cancer lineages are Process utilizing autophagic mechanism, Autophagy, and Chromosome organization involved in meiotic cell cycle. Each is linked with H2AC6 in more than 11 cancer types. Because this analysis shows association rather than direction, both H2AC6-to-partner and partner-to-H2AC6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Process utilizing autophagic mechanism grouped by H2AC6-low versus H2AC6-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC6→partner) and Y-score (partner→H2AC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Process utilizing autophagic mechanism →	+0.043	+1.167	<.001	.003	2	12
BREAST	Autophagy →	+0.043	+1.167	<.001	.003	2	12
KIDNEY	Chromosome organization involved in meiotic cell cycle →	-0.161	-1.840	<.001	.001	3	11
SOFT_TISSUE	Telomere maintenance via semi-conservative replication →	-0.101	-1.365	.005	<.001	3	11
SOFT_TISSUE	Nuclear DNA replication →	-0.119	-1.167	.003	.002	2	11
BLOOD_Lymphoma	Protein catabolic process at synapse →	+0.174	+2.324	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,548 associations by consensus.

Process utilizing autophagic mechanism by H2AC6 expression — BREAST

Explore this box plot interactively →