H2AC3P

Across TCGA pan-cancer cohorts, H2AC3P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated H2AC3P data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher H2AC3P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated H2AC3P expression acts as an unfavorable survival marker.

ESCA, THCA, and CHOL are the cancer types where H2AC3P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
THCA	OS	Tertile	IV	0.579	1.000	<.001	30	view →
CHOL	DFS	Tertile	III,IV	0.095	0.562	.021	27	view →
UCEC	DFS	Tertile	All	0.793	0.899	.021	24	view →
STAD	DFS	Tertile	III,IV	0.289	0.618	.020	18	view →
MESO	DFS	Tertile	III,IV	0.043	0.415	<.001	18	view →
CESC	DFS	Tertile	II,III,IV	0.193	0.705	.045	18	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	18	view →
GBM	OS	Tertile	All	0.216	0.427	.048	9	view →
READ	OS	Tertile	III,IV	0.328	0.751	.003	9	view →
LIHC	DFS	Median	III,IV	0.262	0.451	.009	9	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

H2AC3P–ESCA (OS)

Open the ESCA breakdown →