Across TCGA patient cohorts, H2AC18 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,039 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible H2AC18-associated GO terms across cancer lineages are Protein localization to CENP-A containing chromatin, Innate immune response in mucosa, and Organ or tissue specific immune response. Each is linked with H2AC18 in more than 16 cancer types. Because this analysis shows association rather than direction, both H2AC18-to-partner and partner-to-H2AC18 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC18→partner) and Y-score (partner→H2AC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	Protein localization to CENP-A containing chromatin →	+0.072	+0.723	<.001	<.001	3	17
OV	Innate immune response in mucosa →	+0.078	+0.686	<.001	<.001	3	13
LAML	Organ or tissue specific immune response →	+0.054	+0.337	.001	<.001	2	13
STAD	Antimicrobial humoral immune response mediated by antimicrobial peptide →	+0.053	+0.335	<.001	<.001	3	6
LAML	Negative regulation of megakaryocyte differentiation →	+0.062	+0.469	<.001	<.001	1	8
STAD	Protein localization to chromosome, centromeric region →	+0.053	+0.339	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,039 associations by consensus.

Exploration

H2AC18 survival (RNA) · tumor vs normal (RNA) · all H2AC18 data types